The Spanish fortress known as El Morro, south of Santiago, was constructed between 1638 and 1700 and was designed by Giovanni Antonelli, the Italian architect and engineer responsible for fortresses bearing the same name in both Havana and San Juan, Puerto Rico. El Morro was built to ward off pirates (and rebuilt after a 1662 attack by the English pirate Henry Morgan). Today, its solid walls house the Museum of Piracy, its rooms also reflects the main events connected with the naval battle of Santiago de Cuba, episode of the Spanish-Cuban-American in 1898 and photographs related to the events of Maine , the Spanish and U.S. military leaders, Admiral Pascual Cervera and Vice Admiral Sampson and planes and coastal defenses and batteries of El Morro. There are wonderful views from interior rooms, which have wooden floors and stone walls, as well as from various terraces.

The Granjita Siboney Museum is located in the road to Playa Siboney Beach, in the province of Santiago de Cuba. It is the former encampment from where the youngsters that took the Moncada Headquarters, the second military fortress in the city of Santiago de Cuba, on July 26th 1953 left. In the 7 exhibition rooms of this museum you’ll also discover the historic house, the previous preparations to the famous assault, the development and the consequences it had for Cuba. It exhibits valuable documents and personal objects of some of the intrepid young rebels. Among its most valued objects are the semiautomatic M-1 with folded butt used by the revolutionaries during the assault, sports rifle, uniforms, documents, photographs.

The spirit of one of the Caribbean's most vibrant street parties, Santiago's annual July carnival, is recalled in photos and newspaper clippings, floats, costumes, and musical instruments. Late afternoons here give a better sense of what carnival is like; stop by at 4 pm Tuesday through Saturday for a performance by music and dance troupes. The short spectacle of colorful costume, Afro-Cuban rhythms, and stirring song might have you planning your next trip to coincide with the main event. 

The Basilica of Our Lady of Charity of El Cobre, the Patron Saint of Cuba, can be found 27 km from the city centre, in a mining town founded in 1830. The Basilica stands on a gentle hill and contains display cases with items such as the medal received by the writer Ernest Hemingway on being awarded the Nobel Prize for Literature in 1954. The story of the Virgin dates from the early 1600s, when three men in a boat first saw her floating on water during a storm; tradition holds that the Virgin saved the men from certain drowning. Records show that the statue was most likely brought from Spain on order of the then-governor of Cuba, but don't play iconoclast with the millions of faithful who take seriously the Virgin's reputed miraculous powers. Our Lady of Charity of El Cobre was crowned by Pope John Paul II in 1998, during his visit to Cuba. Every 8th of September, her feast day, thousands of pilgrims come here to give thanks and beg favours of the blessed virgin.