Plaza Mayor, in the Historical Centre of Trinidad, is considered the second most significant square in the country, after Cathedral Square in Havana. This square captivates everybody for the Terpsichore sculpture, the dance muse, the white railings with delicate filigrees, the elegant Royal Palms trees and two greyhound guardians. It was restored by the inhabitants, and became the main place for religious processions, patron saint festivities, promenades and commerce. This delightful square is surrounded of colonial buildings:  Iglesia Parroquial de la Santísima Trinidad; the Palace of Count Brunet (now the Romantic Museum); the Museum of Archeology Guamuhaya (former Casa de Padrón); the Museum of Colonial Architecture (former Sanchez Iznaga residence). 

The Museum of Colonial Architecture on the east side of the main square has examples of woodwork, ironwork, stained glass and other items culled from colonial houses. Museum also offers guided tours through the historic streets of Trinidad.

Located a block to the north of the Plaza Mayor in a former convent is the Museo Nacional de Lucha Contra Bandidos (National Museum of the Struggle against Counter-Revolutionaries). The museum exhibits documents the campaign to weed out rebels who hid in the Escambray mountains in the 1960s.

The Museum of Archeology Guamuhaya, founded on May 15th 1976, in a beautiful mansion on the west side of the Plaza Mayor traces pre- and post-Columbian history. It exhibits in chronological order through 8 rooms objects belonging to the aborigines living in the South Central Region of the island of Cuba during the precolumbus era, as well as material evidence of the Colonial period of very diverse origin and a bill from the city of Trinidad and Valle de los Ingenios. Some of these objects are considered unique in Cuba.