The Cathedral of Havana is an iconic work of what is known as Cuban Baroque and the most remarkable of our colonial churches. The glorious baroque facade and asymmetrical bell-towers of the late 18th-century cathedral are the square’s top attraction. Its interior is surprisingly plain, but it once held the remains­ of Christopher Columbus. Religious services are held here. It has been declared a National Monument.

The Museo Alejandro de Humboldt (Alejandro de Humboldt Museum) is located in a Colonial house in Plaza de San Francisco de Asís Square, in Old Havana, Cuba. Its name comes from the German scientist Alejandro von Humboldt, who is seen as the second person to discover Cuba. This is a scientific museum dedicated to biology and its main objective is to preserve research and promote the historical Humboldt’s legacy. This institution enhances the labor of Cuban and international personalities whose contributions are considered relevant for the development of culture in general terms. It exhibits the historical trajectory of the scientific and botanic data he compiled throughout the island at the beginning of the 19th century, as well as a botanic exhibition which is fundamentally made up of ferns. In this museum there is a perfect copy of a Kritosaurus skeleton found in the desert and donated by the Mexican government, as well as an enormous Pterosaur skeleton, which is around 10 meters length. The House also has a conference room with capacity for 100 persons and a specialized library on German literature.

The National Museum of Fine Arts houses Cuba's most important art collections, as well as paintings dating from the 18th to the 21st century and ancient art. The exhibition areas treasure collections of Cuban and European painting, which harmonize with works of art of ancient Greece, Egypt, and Rome. Its valuable assets are divided into two buildings: Cuban Art, just a short walk from the Museum of the Revolution, and Universal Art, in the magnificent building that was once occupied by the Asturian Centre, opposite the Central Park.

The Palacio del Segundo Cabo (Segundo Cabo Palace) is located on the north side of Plaza de Armas Square, Old Havana. This majestic palace is Neoclassical in style and was built in 1772 with local limestone full of holes and calcareous marine incrustations. This building was first built as headquarters of the Spanish vice-governor. Currently, and after several reworkings during which it functioned as Post office, Senate Palace, Supreme Court, National Academy of Arts and Letters, or the Cuba Academy of Science, nowaday it belongs to the Cuban Ministry of Culture, and it hosts the Centre for the Interpretation of Cuba-Europa Relationship.