Located a block to the north of the Plaza Mayor in a former convent is the Museo Nacional de Lucha Contra Bandidos (National Museum of the Struggle against Counter-Revolutionaries). The museum exhibits documents the campaign to weed out rebels who hid in the Escambray mountains in the 1960s.

The Museum of Archeology Guamuhaya, founded on May 15th 1976, in a beautiful mansion on the west side of the Plaza Mayor traces pre- and post-Columbian history. It exhibits in chronological order through 8 rooms objects belonging to the aborigines living in the South Central Region of the island of Cuba during the precolumbus era, as well as material evidence of the Colonial period of very diverse origin and a bill from the city of Trinidad and Valle de los Ingenios. Some of these objects are considered unique in Cuba.

The Valle de los Ingenios, declared World Heritage since 1988, is located about 12 km outside of Trinidad and has been around since the 17th century.  This fertile agricultural land was cultivated and developed into one of the major sugar producing areas of Cuba, helping Trinidad to become one of the richest cities on the Caribbean island. At the top of the "Torre Manacas-Iznaga" (built at the beginning of the 19th century), you can get an overview of the valley. This 45 meter-high structure is equipped with a bell tower that was used to oversee the thousands of slaves working on the sugar plantations.

A block south of Plaza Mayor stands the grand Palacio Cantero, built in 1830. It has a magnificent ladder and great neoclassical paintings performed by local and Italian artists. Painted pillars, scrolls, shells, pediments and drapes embellish the interior, eclipsing the historical artefacts and old furniture that now form the Trinidad's History Museum.