The Cathedral of Havana is an iconic work of what is known as Cuban Baroque and the most remarkable of our colonial churches. The glorious baroque facade and asymmetrical bell-towers of the late 18th-century cathedral are the square’s top attraction. Its interior is surprisingly plain, but it once held the remains­ of Christopher Columbus. Religious services are held here. It has been declared a National Monument.

The vast Fortaleza de San Carlos de la Cabaña, known as ‘La Cabaña’, running beside the harbor, was constructed after the English capture of Havana in 1763. The largest of the military structures built by Spain in the Americas, this fortress was completed in 1774 and its presence formed an effective complete deterrent against the country's enemies. The polygon, occupying an area of around 10 hectares, consists of bastions, ravelins, moats, covered walkways, barracks, squares and stores.  It is impressively well preserved, and the gardens and ramparts are romantically lit in the evening. This fortress hosts the spectacular nightly ceremony of El Cañonazo de las Nueve (cannon fire at 9), the firing of a cannon that marked the closing of the city gates, one of Havana's longest-held and most attractive traditions.

The neighbors of the town insisted to the town council on the need to create a new public square for their amusement. In 1587, the town council decided to use as a public square the area behind the Convento de San Francisco, which was being built at the time. During the latter decades of the 16th century, this square was called the Plaza Nueva (new square), but from the 18th century onwards, once the Plaza del Cristo had been built, it began to become known as the Plaza Vieja (old square). The most remarkable feature of this square are the buildings around it, with their unquestionable historical and artistic importance of having been the blueprint for a style of architecture which, along with certain developments, subsequently spread throughout the city and characterised the Cuban architecture of the 18th century.

The Museo Alejandro de Humboldt (Alejandro de Humboldt Museum) is located in a Colonial house in Plaza de San Francisco de Asís Square, in Old Havana, Cuba. Its name comes from the German scientist Alejandro von Humboldt, who is seen as the second person to discover Cuba. This is a scientific museum dedicated to biology and its main objective is to preserve research and promote the historical Humboldt’s legacy. This institution enhances the labor of Cuban and international personalities whose contributions are considered relevant for the development of culture in general terms. It exhibits the historical trajectory of the scientific and botanic data he compiled throughout the island at the beginning of the 19th century, as well as a botanic exhibition which is fundamentally made up of ferns. In this museum there is a perfect copy of a Kritosaurus skeleton found in the desert and donated by the Mexican government, as well as an enormous Pterosaur skeleton, which is around 10 meters length. The House also has a conference room with capacity for 100 persons and a specialized library on German literature.