The Museo de Arte Colonial (Colonial Art Museum) is housed within the oldest construction in Old Havana, the Condes de Casa Bayona Palace, a mansion rebuilt in 1720 by Cuban Governor, Don Luis Chachón. The palace’s Classical patio and coffered ceiling made intricately of wood stand out within this construction. The palace boasts a wonderful location, right in front of the San Cristóbal de La Habana Cathedral. This small museum has a Colonial furniture and decorative art exhibition, amongst which will stand out some pottery with Colonial Cuba motifs, as well as several scenes of Colonial dining rooms and a fantastic collection of ornamental flowers.

Plaza de Armas surrounds a statue of the patriot Céspedes and is ringed by shaded marble benches and second-hand bookstalls. This square, founding in 1519, was the city's first open space, around which the most important political, military, religious and civil institutions were located. The palaces that surrounded it during the 18th century are worthy exponents of Cuban Baroque architecture. On the square’s eastern side a small neoclassical temple, El Templete, marks the spot where the first Catholic mass was celebrated in 1519. Next door is one of the city’s most luxurious hotels, Hotel Santa Isabel. To the north, the squat but angular and moated Castillo de la Real Fuerza (Fort of the Royal Forces) is one of the oldest forts in the Americas.  

The Templete, a small neo-classical style construction, was built in the second half of the 18th Century. It is located in Plaza de Armas. This was the site where the first public mass was celebrated and also the site of the first town council of the nascent town of San Cristóbal de La Habana. The Templete resembles a Doric temple and houses three commemorative canvasses by the famous French painter Juan Bautista Vermey. One of the walls exhibits the plate that declares Old Havana a World Heritage Site.

A few steps towards Calle Brasil from Plaza del Cristo Square is where the 1886 Museo de la Farmacia Habanera is located. Founded by the Catalonian José Sarrá, it is a shop-museum and nowadays still functions as a pharmacy. The museum displays the history of pharmacies in Havana and their evolution in Cuba. This Pharmacy preserves its original Neo-gothic furniture with Moorish influences, and host a large collection of medicine bottles and medical tools, extracted from archeological excavations in the old city, as well as a book collection with valuable prescriptions for the study of Cuban pharmacopoeia. The museum also exhibits an elegant scale model of an old pharmacy with captivating historical explanations.